CONTINUOUS REAL-TIME REMOTE STRESS-FREE LONG-TERM HOME-CAGE UNDISTURBED NON-INVASSIVE Monitoring of Digital Biomarkers in Group-housed Mice!
For comprehensive understanding of mouse phenotypes, continuous monitoring of their activity and behavior in the absence of external stimuli is crucial. While video-based systems offer remote monitoring, they are expensive, labor-intensive, and prone to experimenter bias as they rely on research staff fully dedicated to video interpretation. Additionally, conventional temperature recording methods, which involve intrusive devices and frequent handling, are stressful for the animals and challenging in group-housed or nocturnal settings.
The UID Mouse Matrix offers an innovative solution designed to overcome the challenges researchers face when monitoring temperature and activity in socially-housed mice. This RFID-enabled system allows continuous and remote tracking of digital biomarkers, such as locomotor activity and temperature, for one or multiple mice within their home-cage environment. The system can monitor group-housed mice 24/7 in a completely undisturbed setting, even during the dark phase. By eliminating experimenter bias and providing real-time data collection, it facilitates frequent and accurate measurements of progressive behavioral and physiological changes in the same animal over time. We partnered with the leading manufacturers of rodent housing systems (Allentown and Innovive) to enable remote monitoring capabilities with high-density IVC rack systems.
The UID Mouse Matrix enables automatic, continuous, and remote monitoring of temperature and activity for group-housed mice while in their home cage environment and without researcher interference.
Convenient and Easy to Use
1. Insert Microchip
Simply insert the miniature microchip in the animals, and place them back in their cage. The UID Temperature-sensing microchip provides mouse tracking capabilities and reliable temperature measurements with unmatched accuracy to ±0.1oC.
2. Place Mouse Matrix Under the Cage
Place the UID Mouse Matrix reader under the cage for continuous (24/7) and undisturbed tracking of the animals’ temperature and activity. The Matrix reader actively polls its antennae (plate zones) to scan the cage for the presence of any microchip within range. Once detected, the microchip activates and sends relevant data (Animal ID, Temperature, Location, Time/Date) to the data collection software. Zone transitioning is done in rapid succession with timing adjusted by the user’s specifications.
3. Collect Data
The UID Matrix Software collects and records the data from the Matrix system(s) as often as every 100-250 milliseconds. The program automatically captures physiological and behavioral biomarkers in real-time (24/7), and these data can be accessed remotely or stored for further analysis.
Compatible with Individually Ventilated Cage (ICV) Housing Systems
UID partnered with the leading manufacturers of rodent housing systems to introduce high-density IVC rack systems fully integrated with real-time, remote monitoring technology
Allentown’s Reusable and Disposable IVC System with Integrated Mouse Matrix Plates
The InnoRack – A High Performance IVC Rack with Integrated Mouse Matrix Plates
Remote & Continuous Monitoring
- Undisturbed rodent behavior
- Evaluation of physiological and behavioral biomarkers
- Accurate measurement of progressive behavioral changes
Automated Data Collection
- Reduce errors inherent in manual data entry
- Eliminate experimenter bias
- Increase accuracy, reproducibility and objectivity
Enhanced Animal Welfare
- Reduce animal handling and stress
- Non-invasive temperature monitoring
- Undisturbed monitoring of mouse activity
- Alerts for critical health indicators
Create your own smart cage system and start monitoring digital biomarkers from your study animals in their home-cage environment, and without disturbing them!
Mouse Matrix Reader Plate
- 6-, 8- or 12-zone configuration
- Thin profile to maximize cage density
- Compatible with static cages and select cage-rack systems
Mouse Matrix Controller
- PC w/ SQL Express
- Up to 190GB data storage
PoE Switch
- 24-port switch, plus all cables
- Power and communication for up to 24 plates
- Multiple devices can be used
Mouse Matrix Software
- Intuitive program provides data graphing and analysis
- Real-time access to data, and export to Excel for further analysis
- Server/client edition
UID Temperature Programmable Microchip
- Miniature RFID transponder with integrated temperature biosensor
- Temperature accuracy: ±0.1°C @ 38°C
- Optimal temperature read range: 25°C – 50°C
Benefits
Features
Mouse Matrix Software Analytics
Continuous Real-time Remote Stress-free Long-term Home-cage Undisturbed Non-invassive monitoring of temperature and activity in group-housed mice!
