Body temperature is one of the fundamental parameters evaluated when determining the health status of an animal in the clinical or research setting. Temperature is also a valuable biomarker to determine humane end points for animal welfare, as well as a useful clinical indicator for evaluating disease onset and progression in infectious disease models.
Although body temperature data is such a useful readout in research studies, it is often not evaluated due to measurement challenges. Rectal thermometry is the most common method used for core temperature measurements, but this technique is not only time- and labor-intensive, but also can lead to significant animal stress due to manual restraint required for insertion of the device. Non-contact infrared thermometry is less invasive, but this method can be influenced by external ambient temperatures, which can lead to inaccurate temperature readings. Therefore, a practical and reliable method for routine temperature measurements in research animals is required.